Shanghai will adjust relevant management measures for inbound personnel

"Shanghai release" WeChat official account news, Shanghai Municipal Leading Group Office for Epidemic Prevention and Control Work released relevant management measures for entry personnel after "Class B and Class B management", as follows:

1、 From 0:00 on January 8, 2023, new arrivals in Shanghai will undergo nucleic acid testing 48 hours before their departure. Those who are negative can come to China. If they are positive, relevant personnel should return to China after turning negative.

2、 From 0:00 on January 8, 2023, the nucleic acid testing and centralized isolation of all personnel after entry will be cancelled. Those whose health declaration is normal and there is no abnormality in the customs port routine quarantine can be released to the public. For personnel with abnormal health declaration or fever and other symptoms, the customs shall conduct antigen testing. If the result is positive, if it is an asymptomatic infected person or a mild case without serious basic diseases, it can be taken at home, isolated at home or self-care. In other cases, it is recommended to go to medical institutions for diagnosis and treatment as soon as possible.

3、 For those who have entered the country and are still under quarantine management in Shanghai, they will complete a nucleic acid test on January 7. If the nucleic acid test results are positive, they can choose to live at home, live in isolation or go to hospital independently; If the nucleic acid test result is negative, the person will be released from isolation and enter the society.

4、 From 0:00 on January 8, 2023, no "health code" will be assigned to inbound personnel; Meanwhile, at 0:00 on January 8, the red code of "health code" of the existing immigration personnel was cancelled.

5、 Subsequently, dynamically adjust the prevention and control measures according to relevant national policies. Please continue to do a good job in personal protection, adhere to the "three pieces" and "five demands". Wear masks regularly, wash hands frequently and ventilate frequently, and keep social distance. The elderly, especially those with basic diseases, should reduce unnecessary going out and strengthen personal protection. Get vaccinated against COVID-19 as soon as possible, and be the first person responsible for your health. (Issued in Shanghai)

But “you gotta be careful when you decide to come back to life,” says Peter Setlow, a biochemist at UConn Health in Farmington. “Because if you get it wrong, you die.” How is a spore to tell?

For spores of the bacterium Bacillus subtilis, the solution is simple: It counts.

These “living rocks” sense it’s time to revive, or germinate, by essentially counting how often they encounter nutrients, researchers report in a new study in the Oct. 7 Science.
“They appear to have literally no measurable biological activity,” says Gürol Süel, a microbiologist at the University of California, San Diego. But Süel and his colleagues knew that spores’ cores contain positively charged potassium atoms, and because these atoms can move around without the cell using energy, the team suspected that potassium could be involved in shocking the cells awake.

So the team exposed B. subtilis spores to nutrients and used colorful dyes to track the movement of potassium out of the core. With each exposure, more potassium left the core, shifting its electrical charge to be more negative. Once the spores’ cores were negatively charged enough, germination was triggered, like a champagne bottle finally popping its cork. The number of exposures it took to trigger germination varied by spore, just like some corks require more or less twisting to pop. Spores whose potassium movement was hamstrung showed limited change in electric charge and were less likely to “pop” back to life no matter how many nutrients they were exposed to, the team’s experiments showed.

Changes in the electrical charge of a cell are important across the tree of life, from determining when brain cells zip off messages to each other, to the snapping of a Venus flytrap (SN: 10/14/20). Finding that spores also use electrical charges to set their wake-up calls excites Süel. “You want to find principles in biology,” he says, “processes that cross systems, that cross fields and boundaries.”